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Handling, storing, or transporting temperature sensitive materials are subject to regulations by government authorities. Almost every regulatory document in the area of good manufacturing practices (GMP) and good distribution practices (GDP) requires the calibration of temperature sensors. This guide gives a compact overview on how to calibrate in compliance with GxP requirements. It addresses the following questions:

• What is a calibration? What do regulations say about calibration and recalibration?
• Should sensors be calibrated during production? What does the calibration certificate entail?
• How can I keep my system compliant (yearly calibration)?
• How do I read an ISO 17025 calibration certificate?